Comparing dichotomous screening tests when individuals negative on both tests are not verified
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چکیده
منابع مشابه
Comparing dichotomous screening tests when individuals negative on both tests are not verified.
Two dichotomous screening tests are often compared by performing both tests in a sampled population, and submitting positive results on either test to verification by the reference standard. Unbiased estimates of the true positive and false positive rates of each test cannot be estimated directly. However, unbiased estimates of the relative true positive and relative false positive rates may be...
متن کاملAnalytic methods for comparing two dichotomous screening or diagnostic tests applied to two populations of differing disease prevalence when individuals negative on both tests are unverified.
Two dichotomous screening tests may be compared by applying both tests to all members of a sampled population. For individuals with a positive result on either test the disease status may be verified by a reference standard, but for individuals negative on both tests the disease status may be unverified because the probability of disease is so low that further investigation is costly, unaccepta...
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BACKGROUND Estimating the disease prevalence and test accuracy (sensitivity and specificity) for two dependent screening tests when the status of individuals who are negative on both tests is unverified represents a considerable challenge, as the disease rates for individuals negative on both tests are not identifiable without additional assumptions. METHODS This article presents a unified fr...
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ژورنال
عنوان ژورنال: Journal of Clinical Epidemiology
سال: 1997
ISSN: 0895-4356
DOI: 10.1016/s0895-4356(97)00122-4